Fig. 1From: Cdk5 regulatory subunit-associated protein 1 knockout mice show hearing loss phenotypically similar to age-related hearing lossCdk5 regulatory subunit-associated protein 1 (CDK5RAP1) mediates 2-methylthio (ms2) modifications in mammalian mitochondrial transfer RNAs. a Central dogma: mt-tRNAs play a crucial role in mitochondrial protein synthesis. b Structures of N6-isopentenyladenosine (A) and 2-methylthio-N6-isopentenyladenosine (ms2A)Back to article page