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Table 1 List of control and Alzheimer’s disease cases, their demographics, APOE genotype, and randomization of samples for Tandem Mass Tag isobaric 10-plex multiplexing

From: APOE genotype dependent molecular abnormalities in the cerebrovasculature of Alzheimer’s disease and age-matched non-demented brains

DX APOE genotype Mean age [years] Male Female N per group TMT 10 Plex labels
Control E2/E2 71.5 ± 8.58 33.3% (2/6) 66.7% (4/6) 6 TMT − 126
Control E2/E3 80 ± 5.85 50% (3/6) 50% (3/6) 6 TMT -127N
Control E3/E3 83 ± 3.04 100% (6/6) 0% (0/6) 6 TMT -127C* (denominator)
Control E3/E4 84.17 ± 3.64 60% (3/5) 40% (2/5) 5 TMT -128N
Control E4/E4 45.83 ± 4.39 66.7% (4/6) 33.3% (2/6) 6 TMT -128C
AD E2/E2 90 ± 17.0* 0% (0/3) 100% (3/3) 3 TMT -129N
AD E2/E3 89 ± 4.14 66.7% (4/6) 33.3% (2/6) 6 TMT -129C
AD E3/E3 87 ± 3.27 16.67% (1/6) 83% (5/6) 6 TMT -130N
AD E3/E4 78.5 ± 3.60 50% (3/6) 50% (3/6) 6 TMT -130C
AD E4/E4 84.8 ± 4.55 40% (2/5) 60% (3/5) 5 TMT -131
Total Control All Genotype 72.90 ± 3.49 37.9% (18/29) 62.1% (11/29) 29 -126, -127N, -127C, -128N, -128C
Total AD All Genotype 85.24 ± 2.10 38.5% (10/26) 61.5% (16/26) 26 -129N, -129C, -130N, -130C, -131