Table 2 Shows the clinical background of patients focusing on brain weight and scores for the mini-mental state examination (MMSE), Amyloid plaque, Tangle, Braak staging, White matter and CAA
DX | APOE genotype | Brain weight | MMSE score | Amyloid plaque score | Tangle score | Braak score | White matter score | CAA score |
|---|---|---|---|---|---|---|---|---|
Control | E2/E2 | 1207.33 ± 45.8 | 29 (from 1 case) | 3.63 ± 2.4 | 3.25 ± 1.8 | 2.75 ± 0.3 | 2.5 ± 1.5 | 4 ± 4 (50%) |
Control | E2/E3. | 1286 ± 48.8 | 28.6 ± 0.94 | 1.66 ± 1.1 | 3.54 ± 0.6 | 2.17 ± 0.4 | 2.5 ± 0.7 | 0 (0%) |
Control | E3/E3 | 1222 ± 34.7 | 28 ± 0.96 | 1.33 ± 1.3 | 2.67 ± 0.79 | 2.17 ± 0.4 | 1.67 ± 0.6 | 2.83 ± 1.9 (40%) |
Control | E3/E4 | 1193.75 ± 82.4 | 28.25 ± 0.3 | 3.75 ± 2.4 | 4.21 ± 0.9 | 3 ± 0.3 | 3.25 ± 1.9 | 0.4 ± 0.4 (20%) |
Control | E4/E4 | 1310 ± 40 | N/A | N/A | N/A | N/A | N/A | N/A |
AD | E2/E2 | N/A | N/A | 7.83 ± 2.4 | 15 (from 1 case) | 5.67 ± 0.3 | 6 (from 1 case) | 12 (from 1 case) |
AD | E2/E3 | 1104.83 ± 80.9 | 18.3 ± 3.0 | 9.3 ± 1.7 | 8 ± 1.1 | 4.16 ± 0.2 | 3.3 ± 0.8 | 4.17 ± 1.7 (60%) |
AD | E3/E3 | 1060 ± 37.9 | 6.67 ± 5.7 | 13.04 ± 0.97 | 10.4 ± 2.12 | 4.67 ± 0.61 | 5.83 ± 1.9 | 3.4 ± 1.3 (66.6%) |
AD | E3/E4 | 1036.8 ± 49.3 | 18 ± 3.2 | 13 ± 0.6 | 13 ± 0.9 | 5.167 ± 0.3 | 2.8 ± 1.3 | 4.6 ± 0.9 (100%) |
AD | E4/E4 | 959 ± 18.1 | 11 ± 2 | 14.25 ± 0.31 | 14.5 ± 0.32 | 6 ± 0 | 6.2 ± 0.9 | 8.33 ± 1.4 (100%) |