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Fig. 3 | Molecular Brain

Fig. 3

From: The physiological role of Homer2a and its novel short isoform, Homer2e, in NMDA receptor-mediated apoptosis in cerebellar granule cells

Fig. 3

NMDAR currents were decreased by overexpression of the N-terminal domain of Homer2a. A Top row: representative NMDA-induced inward current trace from control (non-AdV-infected) CGCs. Middle and bottom rows: representative current traces from CGCs infected with EGFP or Homer2 constructs. Whole cell recordings were performed 48 h after infection. B Quantification of NMDA currents. Infection with H2a-N caused a significant decrease in the NMDA current compared with the EGFP group. E: EGFP, F: H2a-F, C: H2a-C, N: H2a-N. *p < 0.05, one-way ANOVA and post hoc Bonferroni test. n = 3

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Molecular Brain

ISSN: 1756-6606