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Fig. 3 | Molecular Brain

Fig. 3

From: Reductions in midbrain GABAergic and dopamine neuron markers are linked in schizophrenia

Fig. 3

GABAA receptor subunit gene expression in the midbrain in schizophrenia. a GABRA1 mRNA was 43.77% lower in the midbrain from schizophrenia cases compared with controls. b GABRA2 mRNA was 21.53% lower in the midbrain from schizophrenia cases compared with controls. c GABRA5 mRNA showed a decrease of 20.98% in the midbrain of schizophrenia cases compared with controls. Pink dots are low inflammatory/schizophrenia cases, dark red dots are high inflammatory/schizophrenia cases. Reductions in GABRA1, 2 and 5 mRNA levels were not exacerbated by neuroinflammation. Statistical results for analysis by inflammatory subgroup are in Table 3. Bars indicate mean ± SEM. *p < 0.05, ***p < 0.001, ****p < 0.0001

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