Fig. 1

Experimental paradigm of Y-maze apparatus. A Schematic of the experimental configuration (top) and representative images of YFP fluorescence in the CeA, projection site (bottom left), and the PB, injection site (bottom right). The dashed line in the bottom left image indicates the position of the optic fiber. Scale bar, 150 μm. B, C Schematic of the Y-maze apparatus and photostimulation area (B) and wireless LED stimulation system (C). D Schematic illustrations of the CeA and the position of the LED cannula tips for photostimulations. Each circle represents the approximate cannula tip placements (orange, control mice; bule, ChR2 mice). The tip placements of one mouse in the control group was not plotted because some damages in the brain slices made it difficult to estimate the tip positions. E Heatmap showing the time spent in the arms for a mouse during habituation. F, G Summary of the total time spent in each arm (F) and the number of arm entries (G). Circles indicate each mouse. Control, n = 11; ChR2, n = 10. NS, not significantly different (Wilcoxon signed rank test)