Fig. 2

Immobility time of different dosage of interfering peptide. A The immobility time of animals that received a single injection (4 nmol, 2 nmol and 1 nmol of TAT or TAT-α7-peptide i.c.v., and saline i.c.v.) in the FST. FST was performed 1 h after the last injection and was video recorded. Immobility time was recorded manually. Data are presented as mean ± SEM and were analyzed using one-way ANOVA followed by Tukey’s post hoc test (*p < 0.05, **p < 0.01). n = 14 for 2 nmol group and n = 8 for the rest of the groups. B Dose response curve of the interfering peptide on FST immobility time (single injection: 4 nmol, 2 nmol and 1 nmol of TAT or TAT-α7-peptide i.c.v., and saline i.c.v.). FST was performed 1 h after the last injection and the test was video recorded. Immobility time was recorded manually. Data are presented as mean ± SEM. n = 14 for 2 nmol group and n = 8 for the rest of the groups