Fig. 4
From: Disrupting the α7nAChR–NR2A protein complex exerts antidepressant-like effects
TAT-α7-peptide increases ERK1 phosphorylation, but not BDNF expression levels in rat hippocampal tissue. A Representative Western blots of the levels of phosphorylated ERK1/2 in rat hippocampal tissues with TAT peptide and TAT-α7-peptide. The levels of phosphorylated ERK1/2 were normalized after being divided by the level of ERK1/2. B Densitometric analysis of the levels of phosphorylated ERK1 in TAT-α7-peptide group is significantly higher than TAT group (Student’s t-test, **p < 0.01, n = 6). Data were shown as mean ± SEM. C Representative Western blots of the levels of BDNF in rat hippocampal tissues with TAT peptide and TAT-α7-peptide. The levels of BDNF were normalized after being divided by the levels of α-Tubulin. D Densitometric analysis of the levels of BDNF in TAT-α7-peptide group is not significantly different from those in TAT group (Student’s t-test, n = 6). Data were shown as mean ± SEM