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Fig. 9 | Molecular Brain

Fig. 9

From: Meningitic Escherichia coli α-hemolysin aggravates blood–brain barrier disruption via targeting TGFβ1-triggered hedgehog signaling

Fig. 9

SAG treatment showed good BBB protection in response to RS218 infection. A Both pre-treatment (for 12 h) and co-treatment (synchronously) of SAG (10 mg/kg) provided the promising protection in mice against RS218 infection (n = 10). **p < 0.01. B The effect of both SAG treatments (10 mg/kg) on the RS218-caused decrease of ZO-1 in mice brains. C Evan’s blue and IF assays assessing the SAG-induced protective effects on the BBB permeability as well as the preventive effects on the infection-caused ZO-1 reduction, respectively. Scale bar indicated 50 μm

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Molecular Brain

ISSN: 1756-6606