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Fig. 6 | Molecular Brain

Fig. 6

From: Transcriptomic profiling of high- and low-spiking regions reveals novel epileptogenic mechanisms in focal cortical dysplasia type II patients

Fig. 6

Real-time PCR validation of selected DEGs. The expression level of up-regulated mRNAs (TNC, MOBP, CTGF, SLC12A2, GPR37, and KCNK10) and down-regulated mRNA (CARTPT) as identified in the RNAseq data were further validated by real-time PCR. Relative changes in gene expression were calculated using the ΔΔCq method with HPRT as a reference gene. Error bar is mean ± SD based on nine patients and eight control samples, and each sample is analyzed in triplicates. Mean increase in transcripts levels are statistically significant (One-way ANOVA followed by the Tukeys’ post hoc test; *p < 0.05; **p < 0.01; a = MIN vs autopsy, b = MAX vs autopsy; c = MAX vs MIN)

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