Fig. 6

Cav-1 induces the uptake of α-syn regardless of the degradation pathway. Each cell line was cocultured with differentiated A53T-M OE SH-SY5Y cells in the absence or presence of 50 nM bafilomycin A1 using the dual-chamber system. After 24 h of coculture, the samples were stained with mCherry antibody. Scale bar indicates 20 μm. Blue indicates DAPI staining. The intensity was analyzed from five independent experiments. * p < 0.05, **p < 0.01, ***p < 0.001, one-way ANOVA