Fig. 8From: Age-related increase in caveolin-1 expression facilitates cell-to-cell transmission of α-synuclein in neuronsProposed model of the association of cav-1 in the uptake of α-syn. Cav-1 expression increases in the brain with age. Increased cav-1 expression facilitates the uptake of extracellular α-syn, as well as additional Lewy body-like inclusion formation with expressed α-syn inside cells. The phosphorylation of cav-1 is involved in the uptake of α-synBack to article page