Fig. 4
Effects of TPEN on the amplitudes and activation properties of INa in the hippocampal neurons treated with Aβ25–35. a Typical example of INa traces obtained in the hippocampal neurons (left) and record protocol (right). b Maximum current density of INa in the different treatments. c Current voltage (I-V) curves of INa in the different treatments. d Activation curves of INa in the different treatments. e Half-activation potential of INa in the different treatments. f Activation slope factor of INa in the different treatments. The data are presented as means ± SEMs; *p < 0.05 and **p < 0.01 versus the control group; #p < 0.05 versus the Aβ group; n = 21 for the control group; n = 16 for the Aβ group; n = 17 for the Aβ + TPEN group. Aβ amyloid-β, INa, voltage-gated Na+ channel curren