Fig. 5
Effects of TPEN on the inactivation properties of Nav in the hippocampal neurons treated with Aβ25–35. a Typical example of Nav inactivation traces obtained in the hippocampal neurons (left) and record protocol (right). b Inactivation curves of Nav in the different treatments. c Half-inactivation potential of Nav in the different treatments. d Inactivation slope factor of Nav in the different treatments. The data are presented as means ± SEMs; *p < 0.05 and **p < 0.01 versus the control group; #p < 0.05 and ##p < 0.01 versus the Aβ group; n = 18 for the control group; n = 16 for the Aβ group; n = 16 for the Aβ + TPEN group. Nav, voltage-gated sodium channels; Aβ, amyloid-β