Fig. 7

Effects of TPEN on the amplitudes and activation properties of I_A in the hippocampal neurons treated with Aβ_25–35. a Typical example of I_A traces obtained in the hippocampal neurons (left) and record protocol (right). b Maximum current density of I_A in the different treatments. c Current voltage (I-V) curves of I_A in the different treatments. d Activation curves of I_A in the different treatments. e Half-activation potential of I_A in the different treatments. f Activation slope factor of I_A in the different treatments. The data are presented as means ± SEMs; ^*p < 0.05 and ^**p < 0.01 versus the control group; ^#p < 0.05 and ^##p < 0.01 versus the Aβ group; n = 15 for the control group; n = 17 for the Aβ group; n = 9 for the Aβ + TPEN group. Aβ, amyloid-β; I_A, transient outward potassium current