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Fig. 3 | Molecular Brain

Fig. 3

From: Multivalent electrostatic pi–cation interaction between synaptophysin and synapsin is responsible for the coacervation

Fig. 3

Phase separation of Syph Ct alone is driven by tyrosine-tyrosine interactions. a Schematic diagram of Syph Ct WT and 9YS mutant. Y245, Y250, Y257, Y263, Y269, Y273, Y284, Y290, and Y295 were mutated to serine (9YS). b Representative time-lapse fluorescence images of light-activation of Syph Ct 9YS-mCh-CRY2PHR in COS-7 cells. c, d Representative fluorescence image of Syph (Ct)2 9YS-mCer-MP expressed in COS-7 cells (c) and purified Syph (Ct)2 9YS-mCer-MP at 10 μM in vitro in the presence of 3% PEG-8000 (d). Scale bars, 20 μm

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Molecular Brain

ISSN: 1756-6606