Skip to main content
Fig. 4 | Molecular Brain

Fig. 4

From: Multivalent electrostatic pi–cation interaction between synaptophysin and synapsin is responsible for the coacervation

Fig. 4

pi–cation electrostatic interactions govern the coacervating behavior between Syph and positively charged proteins. a Representative fluorescence images of co-condensates formed by purified Syph Ct-mCh and FUS-RBD-mEGFP in vitro. Syph Ct-mCh (5 μM) and FUS-RBD-mEGFP (2.5 μM) were mixed with 5% PEG-8000. b COS-7 cells were transfected with Syph-HA and mCh-Syn (top) or Syph 9YS-HA and mCh-Syn (bottom), and Syph was detected by immunostaining of HA (ICC). Unlike Syph-HA, no droplets were observed with Syph 9YS expression. Scale bars, 20 μm

Back to article page

Molecular Brain

ISSN: 1756-6606