Fig. 1

Sensory and affective characterization of chronic inflammatory pain rats. A Schematic of the experimental timeline. B PWTs of rats that received CFA injections. C Quantification of behavioral parameters in the OF. (a) The percentage of distance in the central zone, (b) time in the central zone, (c) the number of entries into the central zone, (d) and the total distance traveled throughout the arena of the control group and model group. D Quantification of behavioral parameters in the EZM. (a) the percentage of distance in the open arm, (b) time in the open arm, (c) the number of entries into the open arm of the control group and model group. E Quantification of behavioral parameters in the MBT. F Quantification of behavioral parameters in the NSF. (a) the time of latency to feed, (b) and the food consumption. The trajectories of rats in the control group and model group in the OF G on day 29 and EZM (H) on day 30d after CFA injection. All data represent the mean ± SEM, n = 8. **P < 0.01, compared to Control group