Fig. 1

Spatial distribution of BDNF produced synaptic enhancement in the ACC obtaining with multichannel field potential recording. A Schematic diagram and the microphotograph showed the scale of the MED-64 probe (left), location of MED-64 probe on the ACC slice (right). B One example microscopy photograph of the location of ACC slice and MED-64 probe. C A general view of the spatial distribution of the potentials in all active channels within different layers (vertical lines) of one ACC slice at baseline period. D An overview of the spatial distribution of the evoked potentials in all active channels across different layers (vertical lines) of one ACC slice at 3 h after BDNF perfusion. E–G Individual data of changes of the fEPSP slopes with three types of plasticity from one ACC slice of applying BDNF: E Long-lasting synaptic enhancement showing channels; F short-time synaptic enhancement showing channels; G No enhancement showing channels. H Summarized date showed fEPSP slopes from channels with synaptic enhancement after the application of BDNF in one ACC slice