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Fig. 7 | Molecular Brain

Fig. 7

From: Brain-derived neurotrophic factor produced long-term synaptic enhancement in the anterior cingulate cortex of adult mice

Fig. 7

Roles of CP-AMPARs and PKMζ in the expression of BDNF produced synaptic enhancement in the ACC. A Bath applied Ca2+-permeable AMPA antagonist NASPM (50 μM) at 2 h after BDNF perfusion abolished synaptic potentiation in the ACC. B Bar histogram showing the pooled data of fEPSP Slope (%) of NASPM application after BDNF perfusion from six slices of six mice. C Bath applied PKMζ inhibitory peptide ZIP (5 μM) at 2 h after BDNF perfusion also reduced the enhancement in the ACC. D Bar histogram showing the pooled data of fEPSP Slope (%) of ZIP application after BDNF perfusion from six slices of six mice. **p < 0.01 compared with BDNF induced synaptic enhancement, error bars indicated SEM

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Molecular Brain

ISSN: 1756-6606