Fig. 1

Effects of Hypo-Inf and reperfusion on input resistance of hippocampal CA1 neurons. a Sample traces of voltage responses to negative current pulses from − 200 to – 50 pA in 50-pA increments. Scale bars: 10 mV, 200 ms. b I–V relationship during Hypo-Inf and reperfusion. c Input resistance (black, left axis) and AP frequency (purple, right axis) as a function of time during Hypo-Inf and reperfusion. Note that the AP frequency data were reused from our previous study [9]. Error bars represent standard errors. Significance, relative to before, was determined using paired t-tests (*p < 0.05, **p < 0.01)