Fig. 1
From: Association of CaMK2A and MeCP2 signaling pathways with cognitive ability in adolescents
Schematic outline (not to scale) of the Flp-In™ stable cell lines with inducible expression of CaMK2A–DsR fused gene. The CaMK2A–DsR expression cassette is integrated into a distinct Flp recombination target site and is under the control of the Tet repressor. CaMK2A expression is induced by tetracycline. P: promoter; SV40: simian virus 40; CMV: cytomegalovirus; lacZ: β-galactosidase ORF, Amp: ampicillin ORF, DsR: DsRed ORF, pUC ori: Replication origin of plasmid pUC, TetO2: Tetracycline operator 2, and BGH pA: Bovine growth hormone polyadenylation signal