Fig. 1

Schematic diagrams of the experimental protocols. C57BL/6 mice were individually anesthetized via a nose mask. A pair of stainless-steel acupuncture needles were inserted into the murine equivalent of the acupoints: Dazhui (GV14) and Baihui (GV20), or bilateral Tianzong (SI11) (A). B The procedures of RSDS paradigm