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Fig. 10 | Molecular Brain

Fig. 10

From: Electroacupuncture improves repeated social defeat stress-elicited social avoidance and anxiety-like behaviors by reducing Lipocalin-2 in the hippocampus

Fig. 10

Overexpression of lipocalin 2 in the brain induces anxiety-like behaviors in the EPM task. Single intracerebroventricular injection of recombinant lipocalin 2 protein (7 μL, 1 μg/mL) or vehicle in the brain of the mice and the EPM task were performed after 6 days. Time spent in the open arms (A), closed arms (B), or center (C) of the EPM apparatus. D Velocity traveled in the EPM apparatus. Quantitative data are presented as mean ± SEM (n = 5 per group). The Student’s t-test was used to examine the significance of the mean. ** p < 0.01 vs. the vehicle group. EPM: elevated plus maze, LCN2: lipocalin 2, NS: not significant, SEM: standard error of mean

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Molecular Brain

ISSN: 1756-6606