Fig. 2

Electroacupuncture stimulation at the Baihui (GV 20) and Dazhui (GV 14) acupoints improves RSDS-evoked social avoidance behavior. A Representative heat maps for the social activities of each group. After RSDS, the experimental mice were introduced to the social apparatus (Interaction zone: grey area; corner zones: green areas). The time spent in the interaction zone was determined when the target was present (B) or absent (C). D The social interaction ratio was calculated by dividing the time spent in the interaction zone while the target was present by the time spent in interaction zone while the target was absent. The time spent in corners were determined by the interaction zone with target (E) or without target (F). G The velocity traveled with the target present during the test. Quantitative data are presented as the mean ± SEM (control: n = 15; RSDS: n = 15; RSDS/Sham: n = 14; RSDS/EA n = 15). One-way ANOVA with a post-hoc Tukey test was used to examine the significance of the mean. * p < 0.05 vs. the control group. ** p < 0.01 vs. the control group. # p < 0.05 vs. the RSDS group. ## p < 0.01 vs. the RSDS group. NS: not significant