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Fig. 4 | Molecular Brain

Fig. 4

From: Electroacupuncture improves repeated social defeat stress-elicited social avoidance and anxiety-like behaviors by reducing Lipocalin-2 in the hippocampus

Fig. 4

EA stimulation at the Baihui (GV 20) and Dazhui (GV 14) acupoints improves RSDS-evoked anxiety-like behaviors in EPM task. (A) Representative traces for the activity on EPM apparatus for each group. The time spent in open arms (B), closed arms (C), or center (D) of the EPM apparatus were determined. The velocity traveled on the EPM apparatus was measured in (E). Quantitative data are presented as the mean ± SEM (control: n = 11; RSDS: n = 12; RSDS/Sham: n = 14; RSDS/EA n = 11). One-way ANOVA with a post-hoc Tukey test was used to examine the significance of the mean. ** p < 0.01, the RSDS group vs. the control group. # p < 0.05, the EA group vs. the RSDS group. ## p < 0.01, the EA group vs. the RSDS group. ANOVA: analysis of variance, EA: electroacupuncture, EPM: elevated plus maze, NS: not significant, RSDS: repeated social defeat stress, SEM: standard error of mean

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Molecular Brain

ISSN: 1756-6606