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Table 2 ACKR3-Venus expression in the adult mouse peripheral organs

From: Ackr3-Venus knock-in mouse lights up brain vasculature

 

Female

Male

Digestive system

 Stomach

+ + 

+ + 

 Intestine

+ + 

+ + 

 Liver

+ 

n.a

 Pancreas

+ + 

+ + 

 Colon

+ + 

+ + 

Reproductive system

 Uterine Horn

+ + 

n.a

 Testes

n.a

+ + 

 Seminal vesicles

n.a

+ + 

Lymphatic system

 Spleen

+ + + + 

+ + + 

 Thymus

+ 

+ 

Fat

 White fat

+ 

+ 

 Cardio-respiratory system

 Heart

+ 

+ 

 Lung

+ + 

+ + 

Urinary system

 Kidney

+ + + 

+ 

  1. Amplified ACKR3-Venus expression was assessed in adult (P56-P72) animals. Thirteen Ackr3Venus/Venus mouse organs were obtained from females and males. Tissues were immunostained to amplify the Venus tag. Expression in Ackr3Venus/Venus were compared to any background staining observed in Ackr3WT/WT (n = 3) (Additional file 1: Figure S4–S7) organs. The ACKR3 organ expression of Ackr3Venus/Venus are ranked as follows: low (+), moderate (+ +), high (+ + +), very high (+ + + +) expression. This analysis was only qualitative, and no statistical analysis has been done