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Fig. 2 | Molecular Brain

Fig. 2

From: S100B is selectively expressed by gray matter protoplasmic astrocytes and myelinating oligodendrocytes in the developing CNS

Fig. 2

The expression pattern of S100B in the developing CNS. af Sections of E14.5, E16.5, P4, P15, P21 and P72 (adult) mouse spinal cords were subject to anti-S100B immunostaining. S100B+ ventricular cells are indicated with orange arrows (b, c). A few of S100B+ cells were detected both in the white matter (blue arrows) and gray matter (pink arrows) at E16.5 stage (b), but the number increased rapidly at postnatal stages until to P21. g Quantitative comparison of S100B expression in the gray and white matter of spinal cord at different developmental stages. hk The expression of S100B in P0, P4, P7 and P15 forebrain. Orange arrows indicate the ventricular cells. Higher magnification images in the cortex and corpus callosum were shown in (h′k′) and (h″k″), respectively. l, m Quantitative comparison of S100B expression in the corpus callosum and cortex area of forebrain at different developmental stages. sc spinal cord, WM white matter, GM gray matter, DRG dorsal root ganglion, CC corpus callosum. n = 3, *p < 0.05, **p < 0.01. Bar, 100 μm

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