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Table 1 Summary of the main effects of genotype and sAPPα treatment and their interaction on cell differentiation

From: Effect of soluble amyloid precursor protein-alpha on adult hippocampal neurogenesis in a mouse model of Alzheimer’s disease

% Differentiation

Neuronal

Astrocytic

Dependent variable

Genotype

sAPPα

Genotype

sAPPα

GCL

 = 

 = 

 = 

*

DG

 = 

↑/↓a

*

 = 

  1. ↓ denotes reduction; ↑ denotes increase; = denotes no change. aDenotes an interaction between genotype and sAPPα treatment whereby sAPPα tended to increase neuronal differentiation in Tg mice but to decrease it in WT mice. *p < .05. The DG was comprised of the GCL, ML and hilus