% Differentiation | Neuronal | Astrocytic |
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Dependent variable | Genotype | sAPPα | Genotype | sAPPα |
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GCL | = | = | = | ↑* |
DG | = | ↑/↓a | ↓* | = |
- ↓ denotes reduction; ↑ denotes increase; = denotes no change. aDenotes an interaction between genotype and sAPPα treatment whereby sAPPα tended to increase neuronal differentiation in Tg mice but to decrease it in WT mice. *p < .05. The DG was comprised of the GCL, ML and hilus