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Fig. 8 | Molecular Brain

Fig. 8

From: Long non-coding RNA lncC11orf54-1 modulates neuroinflammatory responses by activating NF-κB signaling during meningitic Escherichia coli infection

Fig. 8

Schematic of the molecular mechanism of lncC11orf54-1 in meningitic E. coli-triggered inflammatory responses. Meningitic E. coli infection of hBMECs induces the degradation of lncC11orf54-1 and the production of mgU2-30, while mgU2-30 facilitates the oligomerization and phosphorylation of IRAK1, subsequently promoting the inflammatory responses

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