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Fig. 1 | Molecular Brain

Fig. 1

From: Acute inhibition of OGA sex-dependently alters the networks associated with bioenergetics, autophagy, and neurodegeneration

Fig. 1

Overall protein O-GlcNAcylation is increased in mouse brains exposed to Thiamet G (TG). A Thiamet G increased protein O-GlcNAcylation in broad brain areas. Saline and TG treated mouse brains were dissected and stained with the CTD110.6 anti-O-GlcNAc antibody. B Thiamet G did not change OGT immunostaining. Saline and TG treated mouse brains were dissected and stained with an anti-OGT antibody. C Thiamet G did not change OGA immunostaining. Saline and TG treated mouse brains were dissected and stained with an anti-OGA antibody. No primary antibody slides were used as negative controls. Representative images from each group were shown. Images were shown without nuclear staining except in the TG group (A-C), (n = 3 each). Scale bar = 500 µm

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