Fig. 3

Typical tracing of the heart rate, GCaMP fluorescence, and mCherry fluorescence in a model 1 animal. The time course of the heart rate, GCaMP6 fluorescence, and mCherry fluorescence during cataplexy-like behavior are shown from the top to the bottom. During the 10-h observation period, 25 episodes of cataplexy-like behaviors were observed in this animal. Each record was aligned so that the onset time of cataplexy-like behavior was equal and is shown as overlapping thin lines. The average value from the 25 episodes is shown as a thick line. The cataplexy-like episode lasted 79.8 ± 9.7 s (mean ± SEM, range 27‒209 s, dashed lines indicate the standard error of the mean)