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Fig. 2 | Molecular Brain

Fig. 2

From: Brain region networks for the assimilation of new associative memory into a schema

Fig. 2

Design for the schema training and the critical session, and performance during critical session. A Timeline showing the design of the behavioural experiment including habituation, pre-training, schema training and critical session. PT, probe test; CS, critical session. B Timeline showing procedures on the critical session [white boxes, training of original paired-associates (PAs); yellow boxes, training of new PAs; gray boxes, staying in the home cage; green background, trials for which EGR-1 and ARC expression were measured]. The trained animals were divided into three groups in the critical session (Group OPA, original paired-associates, white; Group NPA, new paired-associates, pink; Group NM, new map, blue; n = 7 in each group). A caged-control (CC) group stayed in a home cage throughout the experiment (n = 7). Recall, cued-recall test; T1-6, trials 1–6; End, collecting the brain sample. C Performance divided between the first 4 (T1-4) and last 2 trials (T5-6) in Groups OPA (white bars), NPA (pink bars) and NM (blue bars) during critical session. A dashed line, chance level. D Cued-recall test 80 min after trial 6. The graph represents percentage dig time at the original cued location (a slash bar), the average of the original non-cued location (white bars), the new cued location (black bars) as well as the average of the new non-cued location (gray bars) in Groups OPA, NPA and NM. A dashed line, chance level. ns, no significance; *p < 0.05; **p < 0.01 versus chance level (t-test). Data are means ± SEM

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