Fig. 9

Reduced number of cortical interneurons in calsyntenin TKO mice. a, b Histological analysis of parvalbumin-positive (PV⁺) neuron numbers at P30. The number of PV⁺ neurons was reduced in the hippocampus and amygdala of TKO mice compared to that in WT mice. Scale bar 20 µm. c, d Histological analysis of PV⁺ neuron numbers at P21. The number of PV⁺ neurons in the TKO mice was comparable to that of PV⁺ neurons in WT mice. The area of the region of the interest was similar between WT and TKO mice at P21 and P30. All data are presented as the mean ± standard error of the mean [P21 (Hippocampus, WT: n = 7, TKO: n = 6; BLA, WT: n = 7, TKO: n = 6) and P30 (Hippocampus, WT: n = 6, TKO: n = 7; BLA, WT: n = 4, TKO: n = 4)]. P values for differences between genotypes were determined using Welch’s t-test (b, d)