Genotype | WT | App-KI | ||||
---|---|---|---|---|---|---|
Anesthesia | Air | Desflurane | Sevoflurane | Air | Desflurane | Sevoflurane |
Measurement | ||||||
 pH | 7.44 ± 0.01 | 7.41 ± 0.02 | 7.47 ± 0.03 | 7.47 ± 0.03 | 7.38 ± 0.00 | 7.46 ± 0.01 |
 pCO2 (mmHg) | 32.28 ± 1.34 | 36.20 ± 2.06 | 33.58 ± 3.17 | 34.43 ± 3.58 | 38.05 ± 0.04 | 30.47 ± 0.91 |
 pO2 (mmHg) | 87.75 ± 3.38 | 91.25 ± 10.18 | 124.50 ± 19.61 | 86.00 ± 1.25 | 85.50 ± 1.77 | 98.00 ± 4.97 |
 BEecf (mmol/l) | − 2.50 ± 1.15 | − 2.00 ± 1.06 | 0.25 ± 0.65 | 0.67 ± 0.72 | − 3.00 ± 0.00 | − 2.33 ± 0.72 |
 \({\text{HCO}}_{3}^{ - }\) (mmol/l) | 21.73±1.04 | 22.83 ± 0.82 | 23.80 ± 0.93 | 24.50 ± 1.11 | 22.45 ± 0.04 | 21.70 ± 0.74 |
 TCO2 (mmol/l) | 22.50 ± 1.15 | 24.00 ± 1.06 | 25.00 ± 0.94 | 25.33 ± 1.19 | 24.00 ± 0.00 | 22.67 ± 0.72 |
 sO2 (%) | 97.25 ± 0.41 | 96.25 ± 1.08 | 98.50 ± 0.75 | 97.00 ± 0.47 | 96.50 ± 0.35 | 98.00 ± 0.47 |
 Na (mmol/l) | 144.50 ± 0.83 | 139.75 ± 1.60 | 143.25 ± 1.08 | 145.67 ± 1.52 | 143.50 ± 1.06 | 140.67 ± 1.09 |
 K (mmol/l) | 4.23 ± 0.16 | 4.38 ± 0.18 | 4.63 ± 0.26 | 4.87 ± 0.12 | 4.20 ± 0.21 | 4.17 ± 0.07 |
 iCa (mmol/l) | 1.08 ± 0.03 | 1.07 ± 0.05 | 1.03 ± 0.04 | 1.12 ± 0.04 | 1.12 ± 0.02 | 0.94 ± 0.03 |
 Glu (mg/dl) | 170.50 ± 23.98 | 194.75 ± 8.22 | 165.75 ± 6.79 | 188.33 ± 15.49 | 170.00 ± 14.85 | 142.33 ± 13.02 |
 Hct (%PCV) | 35.50 ± 1.03 | 34.75 ± 1.52 | 33.50 ± 1.44 | 38.33 ± 1.09 | 39.00 ± 0.71 | 33.67 ± 0.27 |
 Hb (g/dl) | 12.08 ± 0.35 | 11.80 ± 0.53 | 11.43 ± 0.49 | 13.03 ± 0.35 | 13.25 ± 0.25 | 11.47 ± 0.11 |