Fig. 5
From: Chicago sky blue 6B inhibits α-synuclein aggregation and propagation
CSB reduces S129-phosporylated α-synuclein levels and astrogliosis in a transgenic mouse model of synucleinopathy. a, b Representative images showing immunohistochemical staining for S129-phosphoryated α-synuclein (pS129) (a) and GFAP (b). HP, hippocampus; Pfcx, prefrontal cortex. c, d Quantification of pS129 levels in the HP (c) and Pfcx (d). e, f Quantification of GFAP levels in the HP (e) and Pfcx (f). Scale bar: 50 μm. Data are presented as means ± SEM (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; ns, non-significant difference.)