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Fig. 7 | Molecular Brain

Fig. 7

From: Locus specific reduction of L1 expression in the cortices of individuals with amyotrophic lateral sclerosis

Fig. 7

A significant negative correlation in the expression of TARDBP and L1 expression in the motor and frontal cortices. a There was a significant negative correlation between the expression of the major transcript of TARDBP (ENST00000240185.8) and total L1 expression in the motor cortex (ρ = -0.51 p = 3.3 × 10–8). b There was a significant negative correlation between the expression of the major transcript of TARDBP (ENST00000240185.8) and total L1 expression in the frontal cortex (ρ =  − 0.35 p = 0.47). c There was no significant correlation between the expression of the major transcript of TARDBP (ENST00000240185.8) and total L1 expression in the cerebellum (ρ =  − 0.05 p = 0.47). d There was no significant correlation between the expression of the major transcript of TARDBP (ENST00000240185.8) and total L1 expression in the cervical spinal cord (ρ =  − 0.03 p = 0.72). ρ = Spearman’s rank correlation coefficient

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Molecular Brain

ISSN: 1756-6606