Fig. 2

Fear conditioning test. A–D Contextual fear conditioning test. Freezing time during trials are shown. A, C Freezing response in the same chamber as contextual fear conditioning (means ± SEM, n = 8 for p35f/f, CamkII-p35cKO and Dlx- p35cKO mice, ***p < 0.0001, Mann–Whitney U-test). B, D Freezing response with cue test (means ± SEM, n = 8 for p35f/f, CamkII-p35cKO and Dlx- p35cKO mice, ns, not significant, Mann–Whitney U-test). E, F Passive avoidance test. Latency time between door opening and entry into the dark compartment (means ± SEM, n = 8 for p35f/f, CamkII-p35cKO and Dlx- p35cKO mice, ns, not significant, Mann–Whitney U-test)