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Fig. 4 | Molecular Brain

Fig. 4

From: Involvement of Cdk5 activating subunit p35 in synaptic plasticity in excitatory and inhibitory neurons

Fig. 4

Synaptic functions at Shaffer collateral-CA1 pyramidal neuron synapse in Dlx-p35cKO mice. A I–O curve (left) and PPF ratio (right) of the Shaffer collateral-CA1synapse in Dlx-p35cKO and control p35 f/f mice. Synaptic strength was not apparently different, and PPF ratio was not altered in Dlx-p35cKO mice. B LTP induction by TBS was not altered in Dlx-p35 cKO mice. C LTD induction in hippocampal CA1 in P10-18 Dlx-p35 cKO mice resulted in no significant difference from that in p35 f/f mice (n = 5). Top traces indicate overlapped fEPSP wave forms just before and 40 min after LTP induction

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