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Fig. 4 | Molecular Brain

Fig. 4

From: Antiallodynic effects of KDS2010, a novel MAO-B inhibitor, via ROS-GABA inhibitory transmission in a paclitaxel-induced tactile hypersensitivity model

Fig. 4

Comparisons of antiallodynic effects of KDS2010 and PBN on tactile hypersensitivity and ROS. A Effects of PBN on paw withdrawal (%) responses in PTX- and KDS2010-(PTX + KDS) treated mice. The peak effects of PBN did not differ among the groups. B Representative images of DHE staining in the control, PTX-, and KDS2010 (PTX + KDS)-treated mice. Scale bars = 100 µm (left) and 25 µm (right) C Bar graphs of DHE intensity. All data are presented as mean ± SEM. *P < 0.05, **P < 0.01 compared to the respective control

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