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Fig. 7 | Molecular Brain

Fig. 7

From: Antiallodynic effects of KDS2010, a novel MAO-B inhibitor, via ROS-GABA inhibitory transmission in a paclitaxel-induced tactile hypersensitivity model

Fig. 7

KDS2010 treatment had limited side effects on essential brain functions. A The fixed-speed rotarod test was performed in 5-min sessions. Summary bar graphs showing latency to a fall in the controls and mice treated with different concentrations of KDS2010 (PTX + KDS). B Working memory was assessed using a Y-maze apparatus. Percentages of spontaneous alterations are shown by bar graphs. C Locomotor activity was assessed using an open field test. Summary data showing the total distance travelled and D time spent in the center of the maze by each group. All data are presented as mean ± SEM

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Molecular Brain

ISSN: 1756-6606