Fig. 1

LncRNA profile based on RNA-seq data. A Distribution of all identified lncRNAs in TBI samples. B Volcano plot of DElncRNAs in mice cortex 24 h post-TBI compared with control cortex. Red points represent upregulated DElncRNAs and blue points represent downregulated DElncRNAs in TBI group. The genesymbols of ten upregulated lncRNAs and ten downregulated lncRNAs with the most significant expression differences are shown in the plot. C Hierarchical cluster heatmaps of DElncRNAs. Each row represents an RNA, and each column represents a sample. Red indicates relatively high expression, and blue indicates relatively low expression. D Distribution of DElncRNAs in TBI, showing upregulated (gray) and downregulated (black) lncRNAs in each chromosome (chr)