Fig. 3
From: Increased spine PIP3 is sequestered from dendritic shafts
Spatiotemporal PIP3 dynamics at dendritic spines and shafts in response to glutamate administration. A Fluorescence lifetime imaging of FLIMPA3 during glutamate administration. White arrows indicate dendritic spines. The fluorescence lifetime values of dendritic shafts corresponding to dendritic spines were analyzed from the regions indicated by white rectangles in the image before glutamate stimulation. White bar = 1 µm. B Time course of fluorescence lifetime changes in FLIMPA3 in dendritic spines and dendritic shafts. Asterisks denote a statistically significant difference in the fluorescence lifetime difference between dendritic spines and shafts (p < 0.05)