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Fig. 3 | Molecular Brain

Fig. 3

From: High glucose and palmitic acid induces neuronal senescence by NRSF/REST elevation and the subsequent mTOR-related autophagy suppression

Fig. 3

Inhibition of autophagy aggravates senescence-like phenotypes in neurons (ac) Western blotting image of p62, p21 and γH2A.X in PC12 cells under the treatment of DMSO and MHY1485 (10 µmol, 4 h). Data are mean ± SD. n = 3 independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. Unpaired t test for (a), (b) and (c)

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