Fig. 2

Licking responses in early and late stages of training in the head-fixed temporal conditioning task. A Example of the performance of a mouse in early session of the training (session 2; N = 1, 250 trials). B Example of the performance of a mouse in late session of the training (session 10; N = 1, 250 trials). Top: Raster plot of licking responses in a session. The vertical axis indicates the number of trials, and the horizontal axis indicates the time from the reward delivery. Bottom: Histogram of the licking responses in a session. The vertical axis indicates the licks per second and the horizontal axis indicates the time from the reward delivery. C Summary of the performance of mice in early session of the training (session 2; N = 6, 250 trials each). “Anticipatory” indicates anticipatory licking. “Con” indicates consummatory licking. D Summary of the performance of mice in late session of the training (session 10; N = 6, 250 trials each). “Anticipatory” indicates anticipatory licking. “Con” indicates consummatory licking. E Comparison of the performance between early and late sessions of the training. Left: Comparison of the performance of anticipatory licking between early and late sessions of the training (N = 6, 250 trials each, **p < 0.01). Right: Comparison of the performance of anticipatory licking between early and late sessions of the training (N = 6, 250 trials each, “n.s.” indicates not significant). Error bars indicate standard error of the mean