Fig. 1
From: Olfactory marker protein contains a leucine-rich domain in the Ω-loop important for nuclear export
OMP occasionally enters the nucleus in neurons and cultured cells. a, b OMP-IR in the mouse olfactory epithelium (OE). OMP-IR was detected in the cytosol from dendritic knob to somas. OMP-IR was usually not detected in the nuclei of ORNs (a), but some ORNs exhibited OMP-IR inside nuclei. c, d Closed views of ORNs with OMP (c) exclusively in the cytosol or occasionally (d) in the nucleus. Note that OMP-IR even in the nucleus was excluded from dense nuclear foci in diamidino-2-phenylindole (DAPI) staining (white arrow). e OMP-IR was detected in neurons in the paraventricular nucleus (PV) of the hypothalamus. f, g Close views of neurons in the paraventricular neurons with OMP-IR f exclusively in the cytosol or g in both the cytosol and the nucleus. 3V, third ventricle. h, i OMP-IR in HEK293T cells. OMP-IR was detected either h exclusively in the cytosol or i in both the cytosol and the nucleus. The cells with OMP-IR in the cytosol or in the nucleus are labelled with an open star or N, respectively, in a–i