Inactivation | Recovery from inactivation | |||||||
---|---|---|---|---|---|---|---|---|
CaV3.2 | V0.5 (mV) | p | k (mV) | p | (n) | τ (ms) | p | (n) |
WT | − 61.61 ± 1.75 | − 4.48 ± 0.22 | 19 | 644 ± 49 | 15 | |||
P30L | − 65.95 ± 2.67 | > 0.9999 | − 4.75 ± 0.44 | > 0.9999 | 7 | 705 ± 200 | > 0.9999 | 5 |
S187L | − 70.21 ± 3.99 | 0.8716 | − 4.10 ± 0.34 | > 0.9999 | 7 | 400 ± 39 | 0.6749 | 6 |
I799V | − 64.22 ± 1.71 | > 0.9999 | − 4.27 ± 0.51 | > 0.9999 | 10 | 382 ± 76 | 0.1542 | 8 |
A802V | − 70.79 ± 3.80 | 0.3699 | − 4.16 ± 0.39 | > 0.9999 | 6 | 241 ± 28 | 0.0001 | 10 |
E819K | − 65.31 ± 2.86 | > 0.9999 | − 5.18 ± 0.55 | > 0.9999 | 9 | 335 ± 38 | 0.1564 | 5 |
Q1049H | − 65.68 ± 1.74 | > 0.9999 | − 4.44 ± 0.28 | > 0.9999 | 7 | 185 ± 24 | 0.0005 | 5 |
P1120L | − 64.38 ± 3.53 | > 0.9999 | − 3.64 ± 0.57 | > 0.9999 | 7 | 489 ± 197 | 0.4634 | 6 |
P1605H | − 61.32 ± 0.51 | > 0.9999 | − 5.10 ± 0.19 | > 0.9999 | 12 | 470 ± 46 | > 0.9999 | 10 |
R1674H | − 63.29 ± 2.49 | > 0.9999 | − 6.05 ± 1.04 | > 0.9999 | 7 | 397 ± 103 | 0.3918 | 6 |
R1736C | − 62.48 ± 0.73 | > 0.9999 | − 5.50 ± 0.11 | 0.0191 | 12 | 665 ± 68 | > 0.9999 | 7 |
D1779Y | − 64.23 ± 1.07 | > 0.9999 | − 5.03 ± 0.11 | > 0.9999 | 12 | 662 ± 58 | > 0.9999 | 8 |
P2280H | − 74.22 ± 1.89 | 0.0015 | − 4.56 ± 0.37 | > 0.9999 | 10 | 334 ± 42 | 0.0724 | 7 |
E2291K | − 65.27 ± 1.83 | > 0.9999 | − 4.23 ± 0.19 | > 0.9999 | 11 | 429 ± 80 | 0.3967 | 8 |