Fig. 7

Nest building impairment without a social deficit in the 14-3-3γ heterozygous mice. a There was no significant difference in the interaction time (%) in the U-shaped social interaction test (USIT, interaction time [%] = \(\frac{{\text{Time in the stranger mouse area}}}{{\text{Time in the triangle-shaped object }}{\text{me area}}}\) × 100, n = 7 per group). b The 14-3-3γ HET mice shred fewer nestlets than the CTL mice in the nest-shredding test (NST, nestlet shredding [%] = \(\frac{{\text{Nestlet weight}}\,[\text{before}-\text{after}]}{{\text{Nestlet weight}}\,[\text{before}]}\) × 100, n = 8 per group). c, d The nest score (c) and nest height (d) were significantly decreased in the 14-3-3γ HET mice as compared to the CTL mice (n = 7 per group). e Representative pictures of the results for the 14-3-3γ HET mice and CTL mice in the nest-building test (NBT). Results are presented as means ± SEM; *P < 0.05 and **P < 0.01. (HET heterozygous, CTL littermate wild-type control, SEM standard error of the mean)