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Fig. 2 | Molecular Brain

Fig. 2

From: Age-related attenuation of cortical synaptic tagging in the ACC is rescued by BDNF or a TrkB receptor agonist in both sex of mice

Fig. 2

Synaptic tagging was observed in the ACC at different ages in male mice. Summarized plot of the fEPSP slope demonstrates that both strong TBS at site S1 and tagging TBS at site S2. Either adult male mice (n = 5 slices/5 mice) or middle-aged male mice (n = 3 slices/3 mice) could induce L-LTP on site S1 (a). The tagging-like response could be induced in adult male mice (n = 5 slices/5 mice) but not in middle-aged male mice on site S2 (n = 3 slices/3 mice) (b). The fEPSP slope in the last 30 min on site S1 and site S2 in each group (c). Percentage of activated channels that has tagging induced by tagging TBS (d) (**p < 0.01, Student’s t-test)

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