Fig. 3From: Cancer aggravation due to persistent pain signals with the increased expression of pain-related mediators in sensory neurons of tumor-bearing miceGene expression analysis of lumbar DRG in tumor-bearing mice. A The mRNA levels of Vegfa, Gdnf, Bdnf, Ngf, Tac1 and Calca in the lumbar DRG at 15 days after LLC implantation were measured by RT-qPCR (n = 7, unpaired t-test, *p < 0.05 vs. Control + LLC). B Correlation between the mRNA levels of Calca in the lumbar DRG at 15 days after LLC implantation and tumor volume (r = 0.6108, p = 0.0203). The data were subjected to a comparative analysis by testing the null hypothesis for the Pearson product moment correlation. Each dot represents an individual mouse, and the line represents the regression lineBack to article page